International Diabetes News
Scientists find hidden pathways pancreatic cancer uses to spread
A new study from Brazil, published in the journal Molecular and Cellular Endocrinology, sheds light on how pancreatic cancer gains the ability to spread at an early stage. Researchers found that a protein called periostin, along with stellate cells in the pancreas, plays a crucial role in helping cancer cells invade nearby nerves.
Blockbuster weight loss drugs like Ozempic deliver big results but face big questions
Three recently released Cochrane reviews conclude that GLP-1 medications, such as Ozempic, can lead to meaningful weight loss. However, the findings also highlight concerns about the heavy involvement of drug manufacturers in many of the studies. The World Health Organization (WHO) commissioned the reviews to help shape upcoming global guidelines on using these medications to treat obesity.
Negative workplace treatment affects 40% of employees living with diabetes
Two-fifths [40%] of employees living with diabetes reported negative treatment in the workplace because of their condition, according to a new global study conducted by the International Diabetes Federation (IDF). To mark World Diabetes Day on 14 November, the Federation is highlighting the stigma, discrimination and lack of structural support that people living with diabetes continue to face at work.
Scientists found a sugar that could defeat deadly superbugs
Researchers in Australia have developed a promising new strategy to combat deadly bacteria that no longer respond to antibiotics. The team engineered antibodies that lock onto a sugar found only on bacterial cells, an approach that could support a new generation of immunotherapies for multidrug resistant infections acquired in hospitals.
Following the EAT-Lancet diet lowers chronic kidney disease risk
Chronic kidney disease (CKD) is a major issue among adults, affecting approximately 10 % of people worldwide. A recent paper in CMAJ explored the association of this disorder with the EAT-Lancet planetary health diet. Scientists estimate that CKD will be the fifth leading cause of death by 2040. Dietary intake is a major potential risk factor, and various diet plans have been assessed for their associations with reduced CKD risk.
One in two people facing cataract blindness need access to life-changing surgery
The World Health Organization (WHO) is urging countries to accelerate efforts to ensure that millions of people living with cataract can access simple, sight‑restoring surgery – one of the most effective and affordable interventions to prevent avoidable blindness. A new study published today in The Lancet Global Health highlights the scale of the challenge: nearly half of all people across the world facing cataract‑related blindness still need access to surgery.
National childhood type 1 screening is effective and could prevent thousands of emergency diagnoses
Our landmark ELSA study (Early Surveillance for Autoimmune diabetes) has shown that childhood screening for type 1 diabetes works. The findings from ELSA’s first phase signal a major step towards a future in which type 1 diabetes can be detected early, managed proactively, and potentially delayed through immunotherapy. Building on this, we’ve launched the next phase of ELSA – expanding screening to include all children aged 2 to 17 years.
Clinical Trials
Clinical trials are conducted to collect data regarding the safety and efficacy of new drug and device development. There are several steps and stages of approval in the clinical trials process before a drug or device can be sold in the consumer market, if ever.
You can search for some available information on clinical trials
You can search for some available information on clinical trials
This study aims to culturally adapt an existing American Diabetes Association (ADA)-recognized diabetes self-management and support or DSMES (Diabetes Self Management Education Support) program (Project Dulce) and integrate an evidence-based text messaging program (Dulce Digital) for implementation in Filipino Americans (FAs) with type 2 diabetes mellitus (T2DM).
Cholesterol Lowering and Residual Risk in Diabetes, Type 1 (CHORD1)
This is a prospective, interventional, cohort study, meaning that researchers will follow and observe a group of enrolled study participants over a period of time (one to two months) to gather information and record any developments of the outcomes in question.
Precision Dosing of Metformin in Youth With T2D (PRECISE_T2D)
The purpose of this study to compare the typically prescribed dose of metformin (1000mg twice a day) with a higher dose of metformin (1350mg twice a day).
A Study to Better Understand the Role of the Hormones Glucagon and Insulin in the Progression of Diabetes
The purpose of this study is to determine the longitudinal effect of diabetes-associated variation in TCF7L2 on a-cell function and the contribution of a-cell function to longitudinal glucose tolerance and EGP in non-diabetic subjects.
Sources: ClinicalTrials.gov and MayoClinic
You can search for some available information on clinical trials