International Diabetes News

This Week’s News

Diabetes Drug Reduces Knee Arthritis Pain in People With Obesity

Metformin reduces knee pain in people with osteoarthritis and excess weight, offering a low-cost alternative that may delay knee replacement surgery. A commonly used diabetes medication, metformin, can ease knee pain in people with osteoarthritis who are also overweight or obese, and may help postpone the need for knee replacement surgery, according to findings led by Monash University. Metformin, which is commonly prescribed to treat type 2 diabetes, reduced knee arthritis pain over six months in a clinical trial published in JAMA. The randomised clinical trial looked at whether metformin, compared to a placebo, reduced knee pain in patients with symptomatic knee osteoarthritis (knee OA) and overweight or obesity.

Many diabetes medications, birth control now free for Islanders under new pharmacare deal

As of this week, Prince Edward Island residents can access a range of birth control products and diabetes medications and supplies for free through the new national pharmacare program. The agreement, announced in March, will see the federal government pay $30 million over four years to cover costs for drugs and supplies effective May 1. P.E.I. residents with a valid health card are covered automatically. I believe it will benefit about 41,000 Islanders for contraceptives and about 16,000 people who have diabetes on P.E.I.,” P.E.I. Health Minister Mark McLane said in the legislature Thursday. “We’re very proud that we were able to get that deal done with the federal government.”

Black coffee improves insulin sensitivity in women, study finds

A large Korean study shows that drinking black coffee, especially among women, is linked to better glucose control and reduced insulin resistance, highlighting coffee’s potential role in metabolic health. A recent study published in Nutrients explores the association between coffee consumption and glucose metabolism in Korean adults. Coffee is one of the most popular beverages worldwide; however, existing studies have reported mixed results on its health impact. Although each additional cup of coffee has been suggested to reduce the risk of type 2 diabetes mellitus (T2DM) by 6%, irrespective of the presence of caffeine, the mechanisms involved in this association remain unclear. Previous in vitro and in vivo studies have reported that coffee’s abundant polyphenols can improve insulin sensitivity, which is crucial for diabetes management to reduce insulin resistance (IR).

Diet, exercise combined best for tackling belly fat in kids: study

Australian researchers say the best way to reduce excess tummy fat in children is through a mix of healthy eating and regular physical activity. Combining diet and exercise was significantly more effective at reducing central obesity than either approach alone, according to a study released on Saturday, which analyzed data from 34 clinical trials involving over 8,100 children aged 5 to 18. Central obesity, which refers to fat stored around the stomach and internal organs, is considered more dangerous than general obesity due to its link to heart disease, diabetes, and other long-term health issues, said the researchers from Charles Sturt University and Western Sydney University.

Should Insurance Cover Obesity Medications? Older Adults Weigh In

Obesity is a widespread public health concern, with nearly 50% of U.S. adults projected to be obese by 2030. For older adults, managing weight is especially important due to the increased risk of obesity-related conditions like diabetes, heart disease, and sleep apnea. A recent survey involving 2,657 U.S. adults aged 50 to 80 years revealed significant interest in weight management medications (WMMs) and mixed opinions on insurance coverage.The study found that 35.1% of participants were interested in using WMMs. However, among those with a BMI of 30 or greater (classified as obese), the interest surged to 59.1%. Notably, while most participants (75.7%) favored Medicare coverage for these medications, only 30.2% were willing to pay higher Medicare premiums to guarantee coverage.

Clinical Trials

Clinical trials are conducted to collect data regarding the safety and efficacy of new drug and device development. There are several steps and stages of approval in the clinical trials process before a drug or device can be sold in the consumer market, if ever.

You can search for some available information on clinical trials
This study aims to culturally adapt an existing American Diabetes Association (ADA)-recognized diabetes self-management and support or DSMES (Diabetes Self Management Education Support) program (Project Dulce) and integrate an evidence-based text messaging program (Dulce Digital) for implementation in Filipino Americans (FAs) with type 2 diabetes mellitus (T2DM).

Cholesterol Lowering and Residual Risk in Diabetes, Type 1 (CHORD1)

This is a prospective, interventional, cohort study, meaning that researchers will follow and observe a group of enrolled study participants over a period of time (one to two months) to gather information and record any developments of the outcomes in question.

Precision Dosing of Metformin in Youth With T2D (PRECISE_T2D)

The purpose of this study to compare the typically prescribed dose of metformin (1000mg twice a day) with a higher dose of metformin (1350mg twice a day).

A Study to Better Understand the Role of the Hormones Glucagon and Insulin in the Progression of Diabetes

The purpose of this study is to determine the longitudinal effect of diabetes-associated variation in TCF7L2 on a-cell function and the contribution of a-cell function to longitudinal glucose tolerance and EGP in non-diabetic subjects.

Sources: ClinicalTrials.gov and MayoClinic

You can search for some available information on clinical trials